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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD7
All Species:
6.97
Human Site:
S542
Identified Species:
15.33
UniProt:
Q6ZUT3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZUT3
NP_919253.1
714
81614
S542
P
R
N
I
R
M
K
S
F
Q
Q
D
L
Q
V
Chimpanzee
Pan troglodytes
XP_001142428
1045
118548
L580
E
D
A
M
P
E
A
L
K
S
L
I
F
P
N
Rhesus Macaque
Macaca mulatta
XP_001095803
714
81414
S542
P
R
N
I
R
M
K
S
F
Q
Q
D
L
Q
G
Dog
Lupus familis
XP_549262
787
88688
D619
R
M
K
S
F
Q
Q
D
F
Q
E
L
Q
E
A
Cat
Felis silvestris
Mouse
Mus musculus
A2AD83
703
80312
A542
D
L
Q
E
L
Q
E
A
M
A
R
T
S
G
R
Rat
Rattus norvegicus
Q9WTP0
879
98224
S639
A
F
E
D
F
S
R
S
L
P
E
L
D
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506249
1047
119790
T580
K
D
D
S
M
P
E
T
L
K
N
L
I
F
S
Chicken
Gallus gallus
XP_426268
693
77887
L530
S
S
T
W
M
G
E
L
Q
H
E
A
S
H
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O57457
619
70690
Q459
G
Q
T
A
D
D
A
Q
A
N
K
Q
H
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
E662
K
C
Q
P
R
L
N
E
G
D
Q
V
L
F
I
Sea Urchin
Strong. purpuratus
XP_792466
1673
187206
G636
L
E
D
I
E
T
E
G
D
R
E
G
E
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
31.9
95.3
79
N.A.
85.1
23.8
N.A.
30.7
65.5
N.A.
24.2
N.A.
N.A.
N.A.
22.8
20.8
Protein Similarity:
100
44.7
96.5
82.8
N.A.
90
37.6
N.A.
44.8
75.9
N.A.
43.5
N.A.
N.A.
N.A.
38.5
30.2
P-Site Identity:
100
0
93.3
13.3
N.A.
0
6.6
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
6.6
93.3
33.3
N.A.
20
26.6
N.A.
33.3
13.3
N.A.
20
N.A.
N.A.
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
10
0
0
19
10
10
10
0
10
0
0
10
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
19
10
10
10
0
10
10
10
0
19
10
10
10
% D
% Glu:
10
10
10
10
10
10
37
10
0
0
37
0
10
10
0
% E
% Phe:
0
10
0
0
19
0
0
0
28
0
0
0
10
19
0
% F
% Gly:
10
0
0
0
0
10
0
10
10
0
0
10
0
10
19
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
10
10
0
% H
% Ile:
0
0
0
28
0
0
0
0
0
0
0
10
10
0
10
% I
% Lys:
19
0
10
0
0
0
19
0
10
10
10
0
0
0
0
% K
% Leu:
10
10
0
0
10
10
0
19
19
0
10
28
28
0
0
% L
% Met:
0
10
0
10
19
19
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
19
0
0
0
10
0
0
10
10
0
0
0
10
% N
% Pro:
19
0
0
10
10
10
0
0
0
10
0
0
0
10
0
% P
% Gln:
0
10
19
0
0
19
10
10
10
28
28
10
10
19
0
% Q
% Arg:
10
19
0
0
28
0
10
0
0
10
10
0
0
19
28
% R
% Ser:
10
10
0
19
0
10
0
28
0
10
0
0
19
0
10
% S
% Thr:
0
0
19
0
0
10
0
10
0
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _